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EOMES antibody (Eomesodermin) (N-Term)

Details for Product anti-EOMES Antibody No. ABIN357827, Supplier: Log in to see
Antigen
  • EOMES
  • tbr2
  • xeomes
  • eom
  • eomes
  • TBR2
  • C77258
  • TBR-2
  • Tbr2
Epitope
N-Term
41
18
5
4
3
2
2
2
2
1
1
1
1
Reactivity
Human
78
21
3
2
1
Host
Rabbit
57
19
9
3
2
Clonality
Polyclonal
Conjugate
This EOMES antibody is un-conjugated
6
5
5
4
4
4
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
67
45
20
12
3
3
2
1
1
1
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EOMES.
Isotype Ig
Specificity This antibody detects EOMES (N-term).
Purification Protein A Chromatography followed by peptide affinity purification.
Alternative Name EOMES / TBR2 (EOMES Antibody Abstract)
Background This protein is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation.Synonyms: Eomesodermin homolog, T-box brain protein 2, T-brain-2
Molecular Weight 72613 Da
Gene ID 8320, 9606
UniProt O95936
Application Notes ELISA: 1/1,000. Western blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-EOMES antibody (Eomesodermin) (N-Term) (ABIN357827) anti-Eomesodermin (EOMES) (N-Term) antibody
Background publications Baala, Briault, Etchevers et al.: "Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis." in: Nature genetics, Vol. 39, Issue 4, pp. 454-6, 2007 (PubMed).

Intlekofer, Takemoto, Wherry et al.: "Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin." in: Nature immunology, Vol. 6, Issue 12, pp. 1236-44, 2005 (PubMed).

Kimura, Nakashima, Ueno et al.: "A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain." in: Brain research. Developmental brain research, Vol. 115, Issue 2, pp. 183-93, 1999 (PubMed).

Yi, Terrett, Li et al.: "Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19." in: Genomics, Vol. 55, Issue 1, pp. 10-20, 1999 (PubMed).