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CLIC4 antibody (Chloride Intracellular Channel 4)

Details for Product anti-CLIC4 Antibody No. ABIN359726, Supplier: Log in to see
Antigen
  • clic4
  • MGC89006
  • MGC79614
  • CLIC4
  • DKFZp459A0325
  • xclic4
  • CLIC4L
  • H1
  • MTCLIC
  • huH1
  • p64H1
  • cb142
  • wu:fb33c05
  • wu:fc30h10
  • D0Jmb3
  • TU-74
  • mc3s5
  • mtCLIC
Reactivity
Human
86
51
47
6
2
1
1
1
1
1
1
Host
Rabbit
74
19
5
Clonality
Polyclonal
Conjugate
This CLIC4 antibody is un-conjugated
8
5
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
72
51
32
21
18
11
5
3
2
1
Supplier
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Immunogen This antibody is generated from rabbits immunized with recombinant human CLIC4 protein.
Isotype Ig
Specificity This antibody reacts to CLIC4.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name CLIC4 (CLIC4 Antibody Abstract)
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).Synonyms: Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, mc3s5, mtCLIC, p64H1
Gene ID 25932, 9606
UniProt Q9Y696
Research Area Signaling, Metabolism, Cell Cycle, Apoptosis/Necrosis
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CLIC4 antibody (Chloride Intracellular Channel 4) (ABIN359726) Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CLIC4...
Western Blotting (WB) image for anti-CLIC4 antibody (Chloride Intracellular Channel 4) (ABIN359726) Western blot analysis of CLIC4 (arrow) using rabbit polyclonal CLIC4 Antibody.293 cel...
Background publications Singh, Cousin, Ashley: "Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin." in: The FEBS journal, Vol. 274, Issue 24, pp. 6306-16, 2007 (PubMed).

Suh, Crutchley, Koochek et al.: "Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 1, pp. 121-31, 2007 (PubMed).

Hales, Luzio, Chandler et al.: "Localization of calcium in the smooth endoplasmic reticulum of rat isolated fat cells." in: Journal of cell science, Vol. 15, Issue 1, pp. 1-15, 1974 (PubMed).