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Antibodies
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anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (N-...
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) (N-Term) antibody
| Antigen |
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| Synonyms |
ERBB3 |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Western Blotting (WB) (56), Immunoprecipitation (IP) (47), Immunofluorescence (IF) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (32), Flow Cytometry (FACS) (27), ELISA (19), Enzyme Immunoassay (EIA) (15), Immunohistochemistry (IHC) (12), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), ELISA (Detection) (2), Functional Studies (Func) (1), Immunocytochemistry (ICC) (1)
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| Catalog no. |
ABIN359844 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
285.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: ERBB-3, c-erbB-3, HER-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cellsurface receptor HER3, Proto-oncogene-like protein c-ErbB-3
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Alternative name
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ERBB3 / HER3
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Gene ID
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2065
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Swiss-Prot
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P21860
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the N-terminal region of human ErbB3.
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Cross-Reactivity
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Human, Mouse (Murine)
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Isotype
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Ig (Matching secondary antibodies)
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Description
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ErbB3, a member of the EGF receptor family, binds and is activated by neuregulins andNTAK. It potentially forms a heterodimer with each of the other ERBB receptors. This proteinis predominantly expressed in epithelial tissues and brain. The cytoplasmic part of thereceptor may interact with the SH2 or SH3 domains of many signal-transducing proteins. Ligand-binding may increase phosphorylation on tyrosine residues and promote itsassociation with the p85 subunit of phosphatidylinositol 3-kinase ErbB3 is overexpressedin a subset of human mammary tumors.
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Specificity
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This antibody reacts to ErbB3. Species: Human, Mouse. Others not tested.
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Application Notes
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.25 mg/ml
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Purification
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Purified
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Buffer
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PBS with 0.09% (W/V) sodium azide
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Restrictions
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For Research Use only
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Alternatives for antigen "V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3)", type "Antibodies"
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Hosts
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Mouse (74), Rabbit (37), Goat (4)
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Reactivities
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Human (86), Rat (Rattus) (33), Mouse (Murine) (12), Cow (Bovine) (1), Dog (Canine) (1)
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Applications
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Western Blotting (WB) (56), Immunoprecipitation (IP) (47), Immunofluorescence (IF) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (32), Flow Cytometry (FACS) (27), ELISA (19), Enzyme Immunoassay (EIA) (15), Immunohistochemistry (IHC) (12), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), ELISA (Detection) (2), Functional Studies (Func) (1), Immunocytochemistry (ICC) (1)
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Conjugates
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Biotin (6)
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Epitopes
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pTyr1328 (5), N-Term (1)
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