SEMA3A antibody (Middle Region)

Catalog No. ABIN360060

Product Details anti-SEMA3A Antibody

Target: SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA3A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to SEMA3A.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SEMA3A.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SEMA3A

Target: SEMA3A (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A))

Alternative Name: SEMA3A (SEMA3A Products)

Synonyms: COLL1 antibody, HH16 antibody, Hsema-I antibody, Hsema-III antibody, SEMA1 antibody, SEMAD antibody, SEMAIII antibody, SEMAL antibody, SemD antibody, coll-1 antibody, Semad antibody, COLL-1 antibody, SEMA3A antibody, Dsema3a antibody, Sema3A antibody, sema1a antibody, sema3a1 antibody, semaZ1a antibody, sema1b antibody, sema3a2 antibody, semaZ1b antibody, semaphorin 3A antibody, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A antibody, Sema-3a antibody, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa antibody, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab antibody, SEMA3A antibody, Sema3a antibody, Sema-3a antibody, sema3aa antibody, sema3ab antibody

Background: SEMA3A is a member of the semaphorin family with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.Synonyms: SEMAD, Sema III, Semaphorin III, Semaphorin-3A

Gene ID: 10371, 9606

UniProt: Q14563

Pathways: Regulation of Cell Size