PACSIN3 antibody (N-Term)

Catalog No. ABIN360557

Product Details anti-PACSIN3 Antibody

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACSIN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PACSIN3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PACSIN3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PACSIN3

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Alternative Name: PACSIN3 (PACSIN3 Products)

Synonyms: Pacsin1 antibody, wu:fa11d03 antibody, wu:fj67e09 antibody, wu:fq16a06 antibody, zgc:56324 antibody, MGC82145 antibody, PACSIN3 antibody, sdpiii antibody, SDPIII antibody, 4921507A02Rik antibody, 6330413E15Rik antibody, AW413130 antibody, SdpIII antibody, protein kinase C and casein kinase substrate in neurons 3 antibody, protein kinase C and casein kinase substrate in neurons 3 L homeolog antibody, pacsin3 antibody, PACSIN3 antibody, pacsin3.L antibody, Pacsin3 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: Endophilin I, Protein kinase C and casein kinase substrate in neurons protein 3, SH3 domain-containing protein 6511

Gene ID: 29763, 9606

UniProt: Q9UKS6