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Antibodies
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anti-TAR DNA Binding Protein (TARDBP) antibody
TAR DNA Binding Protein (TARDBP) antibody
| Antigen |
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| Synonyms |
ALS10, TDP-43, Tdp43, C85084, 1190002A23Rik, fb77f02, fc52g10, wu:fb77f02, wu:fc52g10, tardbp, MGC53141, TARDBP, TDP43, DKFZp459I2127, MGC129120 |
| Clonality |
Monoclonal (K1B8) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361128 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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TARDBP
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Immunogen
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Recombinant human TARDBP (1-260aa), Accession / GI number: NP_031401
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Isotype
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IgG1, kappa chain (Matching secondary antibodies)
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Clone
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K1B8
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Description
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TAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.
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Application Notes
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Recommended dilution 1:1000(W.B), Recommended dilution 1:100(IHC)
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Hormones, Cytokines
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Restrictions
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For Research Use only
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Alternatives for antigen "TAR DNA Binding Protein (TARDBP)", type "Antibodies"
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Hosts
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Rabbit (21), Mouse (13), Goat (4), Rat (1)
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Reactivities
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Human (36), Mouse (Murine) (9), Rat (Rattus) (8), Cow (Bovine) (1), Dog (Canine) (1)
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Applications
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Western Blotting (WB) (41), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10), Immunohistochemistry (IHC) (9), Enzyme Immunoassay (EIA) (8), Immunofluorescence (IF) (7), Immunocytochemistry (ICC) (2), ELISA (Detection) (1), Immunoprecipitation (IP) (1), siRNA (1)
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Alternatives 
