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Thyroid Hormone Receptor, beta (THRB) antibody
| Antigen | Thyroid Hormone Receptor, beta (THRB) |
| Synonyms |
GRTH, PRTH, THR1, ERBA2, NR1A2, THRB1, THRB2, ERBA-BETA, MGC126109, MGC126110, Nr1a2, Thrb1, Thrb2, T3R[b], T3Rbeta, MGC141269, MGC141270, c-erbAbeta, trb, TR[b]1, TR-beta, fj24f03, wu:fj24f03, THRB, ...
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| Clonality | Monoclonal (2386) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
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| Catalog no. | ABIN361385 |
| Quantity | 100 µl |
| Price | 345.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | Thyroid Hormone Receptor, ß-Isotype |
| Format | Affinity-purified |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | 2386 |
| Description | Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TR 1 and TR 2. TRa1, TR 1 and TR 2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005). Anti-Thyroid Hormone Receptor, -Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR- protein. |
| Specificity | Specific for the ~55k TR-ß protein. |
| Synonyms | GRTH, PRTH, THR1, ERBA2, NR1A2, THRB1, THRB2, ERBA-BETA, MGC126109, MGC126110, Nr1a2, Thrb1, Thrb2, T3R[b], T3Rbeta, MGC141269, MGC141270, c-erbAbeta, trb, TR[b]1, TR-beta, fj24f03, wu:fj24f03, THRB, TR-BETA, LOC734147, thrb |
Application Details
| Application Notes | Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot. |
| Purification | Prepared from mouse ascites by ammonium sulfate precipitation followed by affinity purification on a protein G column. |
| Storage | Store at -20 °C, stable for 1 year |
| Restrictions | For Research Use only |
Images
| Western blots of hippocampal lysate showing specific immunolabeling of the ~58k TR-ß protein. |
Alternatives
Alternatives for antigen "Thyroid Hormone Receptor, beta (THRB)", type "Antibodies"
| Hosts | Rabbit (24), Goat (6), Mouse (5) |
| Reactivities | Human (28), Mouse (Murine) (9), Rat (Rattus) (9), Dog (Canine) (6) |
| Applications | Western Blotting (WB) (23), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Enzyme Immunoassay (EIA) (7), ELISA (6), Immunoprecipitation (IP) (5), Immunofluorescence (IF) (4), Immunohistochemistry (IHC) (3), Electrophoretic Mobility-Shift Assay (EMSA) (2), Immunocytochemistry (ICC) (2), Gel Shift (GS) (1) |
| Epitopes | Isoform beta-1 (3), N-Term (1) |
