THRB antibody (N-Term)

Catalog No. ABIN2779904

This Rabbit Polyclonal antibody specifically detects THRB in WB and ChIP. It exhibits reactivity toward Human, Mouse, Rat, Horse, Guinea Pig and Cow.

Quick Overview for THRB antibody (N-Term) (ABIN2779904)

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Reactivity: Human, Mouse, Rat, Horse, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THRB antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-THRB Antibody

Binding Specificity: N-Term

Purpose: Thrb Antibody - N-terminal region

Sequence: KSKDSDLDMA LSQSSQPAHL PEEKPFPQVQ SPPHSQKKGY IPSYLDKDEL

Predicted Reactivity: Cow: 90%, Guinea Pig: 90%, Horse: 90%, Human: 90%, Mouse: 100%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against Thrb. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Thrb

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113882

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for THRB

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Alternative Name: Thrb

Background:

Background Information: Thrb is high affinity receptor for triiodothyronine.

Gene Name: Thyroid hormone receptor beta

Alternative Symbols: Nr, Nr1a2, T3R[b, T3Rbe, Thrb1, Thrb2, T3R[b], T3Rbeta, c-erbAb, c-erbAbeta

Protein Name: Thyroid hormone receptor beta

Molecular Weight: 52kDa

Gene ID: 21834

NCBI Accession: NP_033406

UniProt: P37244

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound