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Gap Junction Protein, alpha 1, 43kd (GJA1) antibody
| Antigen | Gap Junction Protein, alpha 1, 43kd (GJA1) |
| Synonyms |
CX43, GJAL, ODDD, DFNB38, Cx43, Npm1, Cnx43, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43, Cx32, Cnx32, Gjb-1, MGC6217, AI118175, MGC93610, gja1, cx43a1, zfCx43.3, MGC128721, gja1-A, connexin 43, ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN361422 |
| Quantity | 100 µl (Variants) |
| Price | 345.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | Connexin43 |
| Format | Affinity-purified |
| Description | Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b). Anti-Connexin43 Western blot of rat cerebellar lysate showing specific immunolabeling of the ~43k connexin43 protein. |
| Specificity | Specific for the ~43k connexin43 protein. |
| Synonyms | CX43, GJAL, ODDD, DFNB38, Cx43, Npm1, Cnx43, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43, Cx32, Cnx32, Gjb-1, MGC6217, AI118175, MGC93610, gja1, cx43a1, zfCx43.3, MGC128721, gja1-A, connexin 43, cx43, gjal, oddd, dfnb38, CONNEXIN 43 |
Application Details
| Application Notes | Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot. |
| Purification | Prepared from rabbit serum by affinity purification on a column made with the C-terminal peptide used as antigen. |
| Storage | Store at -20 °C, stable for 1 year |
| Research Area | Extracellular Matrix, Cytoskeleton, Signaling |
| Restrictions | For Research Use only |
Images
| Western blots of rat cerebellar lysate showing specific immunolabeling of the ~43k connexin43 protein. |
Alternatives
Alternatives for antigen "Gap Junction Protein, alpha 1, 43kd (GJA1)", type "Antibodies"
| Hosts | Rabbit (46), Mouse (1) |
| Reactivities | Human (43), Rat (Rattus) (42), Mouse (Murine) (38), Cow (Bovine) (17), Dog (Canine) (16), Chicken (15), Horse (Equine) (2), Pig (Porcine) (1) |
| Applications | Western Blotting (WB) (25), Immunofluorescence (IF) (23), Immunohistochemistry (IHC) (21), Flow Cytometry (FACS) (18), ELISA (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pSer367 (5), Ab-261 (1), N-Term (1), pSer261 (1), pSer368 (1) |
