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Gap Junction Protein, alpha 1, 43kd (GJA1) antibody
| Antigen | Gap Junction Protein, alpha 1, 43kd (GJA1) |
| Synonyms |
CX43, GJAL, ODDD, DFNB38, Cx43, Npm1, Cnx43, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43, Cx32, Cnx32, Gjb-1, MGC6217, AI118175, MGC93610, gja1, cx43a1, zfCx43.3, MGC128721, gja1-A, connexin 43, ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN361422 |
| Quantity | 100 µl (Variants) |
| Price | 345.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business days |
Additional Information
| Alternative name | Connexin43 |
| Format | Affinity-purified |
| Description | Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b). Anti-Connexin43 Western blot of rat cerebellar lysate showing specific immunolabeling of the ~43k connexin43 protein. |
| Specificity | Specific for the ~43k connexin43 protein. |
| Synonyms | CX43, GJAL, ODDD, DFNB38, Cx43, Npm1, Cnx43, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43, Cx32, Cnx32, Gjb-1, MGC6217, AI118175, MGC93610, gja1, cx43a1, zfCx43.3, MGC128721, gja1-A, connexin 43, cx43, gjal, oddd, dfnb38, CONNEXIN 43 |
Application Details
| Application Notes | Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot. |
| Purification | Prepared from rabbit serum by affinity purification on a column made with the C-terminal peptide used as antigen. |
| Storage | Store at -20 °C, stable for 1 year |
| Research Area | Extracellular Matrix, Cytoskeleton, Signaling |
| Restrictions | For Research Use only |
Images
| Western blots of rat cerebellar lysate showing specific immunolabeling of the ~43k connexin43 protein. |
Alternatives
Alternatives for antigen "Gap Junction Protein, alpha 1, 43kd (GJA1)", type "Antibodies"
| Hosts | Rabbit (37), Mouse (2) |
| Reactivities | Human (35), Rat (Rattus) (33), Mouse (Murine) (31), Chicken (15), Cow (Bovine) (15), Dog (Canine) (15) |
| Applications | Western Blotting (WB) (22), Immunofluorescence (IF) (18), Immunohistochemistry (IHC) (17), Flow Cytometry (FACS) (13), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (EM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | pSer367 (5), Ab-261 (1), N-Term (1), pSer261 (1), pSer368 (1) |
