GRIA2 antibody (pSer880)

Catalog No. ABIN361455

Cited in 1 publication. The Rabbit Polyclonal anti-GRIA2 antibody (ABIN361455) specifically detects GRIA2 in WB and ELISA. The antibody is reactive with Rat samples.

Quick Overview for GRIA2 antibody (pSer880) (ABIN361455)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GRIA2 Antibody

Binding Specificity: pSer880

Specificity: Specific for endogenous levels of the ~100 kDa GluR2 protein phosphorylated at Ser880. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Cross-Reactivity: Rat

Predicted Reactivity: human, mouse, non-human primate, Zebrafish

Characteristics: Our GluR2-subunit (Ser880) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects GluR2-subunit (Ser880) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References for anti-GRIA2 antibody (ABIN361455)

Murphy, Tcharnaia, Beshara, Jones: "Cortical development of AMPA receptor trafficking proteins." in: Frontiers in molecular neuroscience, Vol. 5, pp. 65, (2012) (PubMed).

Target Details for GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Alternative Name: GRIA2

Background:

Synonyms: AMPA 2 antibody, AMPA selective glutamate receptor 2 antibody, AMPA-selective glutamate receptor 2 antibody, AMPA2 antibody, GluA2 antibody, GLUR 2 antibody, GLUR B antibody, GluR K2 antibody, GluR-2 antibody, GluR-B antibody, GluR-K2 antibody, GLUR2 antibody, GLURB antibody, Glutamate receptor 2 antibody, Glutamate receptor ionotropic AMPA 2 antibody, Glutamate receptor ionotropic antibody, Gria2 antibody, GRIA2_HUMAN antibody, HBGR2 antibody

Description Logic: Our GluR2-subunit (Ser880) rabbit polyclonal phosphospecific primary antibody is produced . It detects GluR2-subunit (Ser880) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: GRIA2

Molecular Weight: 100 kDa

Gene ID: 29627

UniProt: P19491

Pathways: PI3K-Akt Signaling