GRIA2 antibody (C-Term)
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- Target See all GRIA2 Antibodies
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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Binding Specificity
- C-Term
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GRIA2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- Anti-GluR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with GluR2 from other sources has not been determined. Ion Channels research.
- Immunogen
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Immunogen: GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2.
Immunogen Type: Recombinant Protein
- Clone
- S21-32
- Isotype
- IgG1
- Top Product
- Discover our top product GRIA2 Primary Antibody
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- Application Notes
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-GluR2 Antibody is suitable for use in WB, IHC, IP, and Immuno-gold EM. Expect a band approximately ~90 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
- Alternative Name
- GluR2 (GRIA2 Products)
- Synonyms
- GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
- Background
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Synonyms: Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2
Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium.
Gene Name: GRIA2
- Gene ID
- 2891
- NCBI Accession
- NP_000817
- UniProt
- P42262
- Pathways
- PI3K-Akt Signaling
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