SYN1 antibody (pSer9)
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- Target See all SYN1 Antibodies
- SYN1 (Synapsin I (SYN1))
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Binding Specificity
- pSer9
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYN1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Specific for ~78k synapsin I doublet protein phosphorylated at Ser9. The antibody also weakly labels the ~55k synapsin II protein which has a similar phosphorylation site to that of Ser9 on synapsin I. Immunolabeling is blocked by preadsorption of the antibody with the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Immunolabeling is also completely eliminated by treatment withphosphatase.
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Predicted Reactivity
- bovine, human, Xenopus, zebra fish
- Purification
- Antigen Affinity Purified from Pooled Serum
- Immunogen
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 conjugated to KLH
- Top Product
- Discover our top product SYN1 Primary Antibody
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- Application Notes
- Recommended Dilution: WB: 1:1000 IHC: 1:500 Quality Control: Western blots performed on each lot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- Storage
- -20 °C
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ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).
: "Identification of an endogenous substrate of zebrafish doublecortin-like protein kinase using a highly active truncation mutant." in: Journal of biochemistry, Vol. 147, Issue 5, pp. 711-22, (2010) (PubMed).
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ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).
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- Target
- SYN1 (Synapsin I (SYN1))
- Alternative Name
- SYN1 (SYN1 Products)
- Synonyms
- SYN1a antibody, SYN1b antibody, SYNI antibody, Syn-1 antibody, SYN I antibody, si:dkey-90n12.3 antibody, synapsin I antibody, synapsin I L homeolog antibody, SYN1 antibody, Syn1 antibody, syn1.L antibody, syn1 antibody
- Molecular Weight
- '78 kDa
- Gene ID
- 281510
- UniProt
- P17599
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