BU-1A / B6.1 antibody

Catalog No. ABIN371431

Product Details anti-BU-1A / B6.1 Antibody

Target: BU-1A / B6.1

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This BU-1A / B6.1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Characteristics: Synonyms: B-Cell Marker

Purification: Purified

Immunogen: Bursal cells from one-day-old H. B15 (Bu-1a/b) strain chickens. (Ref. 1)

Clone: AV20

Isotype: IgG1

Application Details

Application Notes: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BU-1A / B6.1

Target: BU-1A / B6.1

Abstract: BU-1A / B6.1 Products

Synonyms: AL022991 antibody, Bub1a antibody, C80208 antibody, D2Xrf87 antibody, BUB1, mitotic checkpoint serine/threonine kinase antibody, BUB1 mitotic checkpoint serine/threonine kinase antibody, Bub1 antibody

Background: The Bu1 [chB6] molecule is expressed on chicken B cells throughout most of their development, as well as on some non lymphoid cells. It has long been used as an allotypic marker in important studies of B cell development, though its function is unknown. It has no recognizable similarity to known mammalian molecules and thus represents a unique B cell marker. Its presence in chickens may be related to differences in the properties of B cell development between chickens and mammalian species. The sequences of the different alleles of this gene revealed a higher level of polymorphism than expected. A restriction fragment length polymorphism linked to the CHB6 gene has been used to determine its location on the linkage map of the chicken genome, which will allow the definitive evaluation of reported associations with disease resistance.Synonyms: B-Cell Marker