KRT8 antibody (C-Term)

Catalog No. ABIN371614

This Mouse Monoclonal antibody specifically detects KRT8 in WB, IHC (fro) and EIA. It exhibits reactivity toward Mammalian.

Quick Overview for KRT8 antibody (C-Term) (ABIN371614)

Target: KRT8 (Keratin 8 (KRT8))

Reactivity: Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: SB37b

Product Details anti-KRT8 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts specifically with Cytokeratin 8 and recombinant C-terminal Keratin 8.

Characteristics: Synonyms: KRT8, CYK8, Cytokeratin-8, CK8, Keratin-8, K8, Cytokeratin endo A, Keratin, type IIcytoskeletal 8

Purification: Purified

Immunogen: Recombinant C-terminal fragment of Keratin 8.

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western Blot: < / = 1-2 μg/mL. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): 10 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts.

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for KRT8

Target: KRT8 (Keratin 8 (KRT8))

Alternative Name: Cytokeratin 8

Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30 % sequence homology. (Ref.1-5) Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 (55 kDa) belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in squamous cell carcinomas.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8

Gene ID: 3856

UniProt: P05787