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AQP2 antibody (N-Term)

AQP2 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN372293
  • Target See all AQP2 Antibodies
    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
    Binding Specificity
    • 21
    • 20
    • 17
    • 16
    • 16
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 108
    • 91
    • 81
    • 15
    • 15
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 126
    • 2
    Rabbit
    Clonality
    • 127
    • 2
    Polyclonal
    Conjugate
    • 46
    • 10
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AQP2 antibody is un-conjugated
    Application
    • 118
    • 41
    • 40
    • 40
    • 29
    • 20
    • 18
    • 18
    • 17
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Aquaporin 2 (N-term).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogen
    Synthetic peptide corresponding to N-terminal residues of Human Aquaporin 2.
    Isotype
    IgG
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    Discover our top product AQP2 Primary Antibody
  • Application Notes
    Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
    Alternative Name
    Aquaporin-2 (AQP2 Products)
    Synonyms
    AQP-CD antibody, WCH-CD antibody, cph antibody, jpk antibody, AQP-2 antibody, aquaporin-2 antibody, aquaporin 2 antibody, aquaporin 2 (collecting duct) antibody, Aqp2 antibody, AQP2 antibody
    Background
    Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0, and Aquaporin 1 have been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal dominant cataract. The lens opacity mutation is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic. Aquaporin 2 is located in the collecting tubule.Synonyms: ADH water channel, AQP-CD, AQP2, Aquaporin-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct
    Molecular Weight
    29 kDa.
    Gene ID
    359
    NCBI Accession
    NP_000477
    UniProt
    P41181
    Pathways
    Response to Water Deprivation
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