RAB3A antibody (N-Term)
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- Target See all RAB3A Antibodies
- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse, Xenopus laevis, Non-Human Primate
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAB3A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody recognizes the ~27k Rab3 protein.
- Cross-Reactivity (Details)
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Species reactivity (expected):Human, Mouse, Xenopus and non-Human Primates.
Species reactivity (tested):Rat. - Purification
- Affinity Chromatography.
- Immunogen
- Peptide corresponding to amino acid residues from the N-terminal region of Rat Rab3, conjugated to keyhole limpet hemocyanin (KLH).
- Isotype
- IgG
- Top Product
- Discover our top product RAB3A Primary Antibody
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- Application Notes
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Target
- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
- Alternative Name
- RAB3A (RAB3A Products)
- Synonyms
- RAB3 antibody, rab3a antibody, zgc:92276 antibody, RAB3A antibody, rab-3a antibody, si:ch211-255d18.4 antibody, zgc:112516 antibody, RAB3A, member RAS oncogene family antibody, RAB3A, member RAS oncogene family, a antibody, RAB3A, member RAS oncogene family L homeolog antibody, RAB3A, member RAS oncogene family, b antibody, RAB3A antibody, Rab3a antibody, rab3aa antibody, rab3a.L antibody, rab3a antibody, rab3ab antibody
- Background
- Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3's are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).Synonyms: RAB3A, RAB3B, RAB3C, RAB3D, Rab-3A, Rab-3B, Rab-3C, Rab-3D, Ras-related protein Rab-3A, Ras-related protein Rab-3B, Ras-related protein Rab-3C, Ras-related protein Rab-3D
- Gene ID
- 25531
- NCBI Accession
- NP_037150
- UniProt
- P63012
- Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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