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SYT1 antibody
SYT1
Reactivity: Human, Rat, Mouse, Cow, Chicken, Non-Human Primate
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SYT1 Antibody
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Target
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SYT1
(Synaptotagmin I (SYT1))
Reactivity
All reactivities for SYT1 antibodies
Human, Rat, Mouse, Cow, Chicken, Non-Human Primate
Host
All hosts for SYT1 antibodies
Rabbit
Clonality
All clonalities for SYT1 antibodies
Polyclonal
Conjugate
All conjugates for SYT1 antibodies
This SYT1 antibody is un-conjugated
Application
All applications for SYT1 antibodies
Western Blotting (WB)
Specificity
This antibody recognizes the ~65k Synaptotagmin I protein.
Cross-Reactivity (Details)
Species reactivity (expected):Human, Mouse, Bovine, Chicken and non-Human Primates. Species reactivity (tested):Rat.
Purification
Affinity Chromatography.
Immunogen
Synthetic peptide corresponding to amino acid residues within the Synaptotagmin-1 protein.
Isotype
IgG
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Discover our top product SYT1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at-20 °C.
Target Details for SYT1
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Target
SYT1
(Synaptotagmin I (SYT1))
Alternative Name
Synaptotagmin-1 (SYT1 Products )
Synonyms
P65 antibody, SVP65 antibody, SYT antibody, CG3139 antibody, D. Syt I antibody, DSYT antibody, DSYT2 antibody, DSypt antibody, DSyt antibody, Dmel\\CG3139 antibody, Droso1 antibody, Dsyt2 antibody, SYT I antibody, SYT1 antibody, Syt antibody, Syt 1 antibody, Syt I antibody, Syt-1 antibody, SytI antibody, dSYT antibody, dsyt1 antibody, dsytI antibody, l(2)23AB1 antibody, l(2)23Ba antibody, l(2)k05909 antibody, syt antibody, syt 1 antibody, syt I antibody, syt-1 antibody, syt1 antibody, sytI antibody, AW124717 antibody, G630098F17Rik antibody, Syti antibody, GB20036 antibody, DKFZP459P193 antibody, svp65 antibody, p65 antibody, wu:fj41c01 antibody, wu:fk56d05 antibody, zgc:92899 antibody, synaptotagmin 1 antibody, Synaptotagmin 1 antibody, synaptotagmin I antibody, synaptotagmin-1 antibody, synaptotagmin, p65 antibody, synaptotagmin Ia antibody, synaptotagmin 1 L homeolog antibody, SYT1 antibody, Syt1 antibody, Tsp_06980 antibody, Tsp_08220 antibody, syt1 antibody, LOC100533340 antibody, syt1a antibody, syt1.L antibody
Background
Synaptotagmin-1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that Synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
Gene ID
6857
NCBI Accession
NP_001129277
UniProt
P21579
Pathways
Synaptic Vesicle Exocytosis , Dicarboxylic Acid Transport
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