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Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (C-Term) antibody

Details for Product No. ABIN374117, Supplier: Login to see
Antigen
  • mal
  • wyatt
  • BACTS1
  • Mal
  • MyD88-2
  • AA407980
  • C130027E04Rik
  • Tlr4ap
  • Wyatt
Alternatives
anti-Human Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein antibody for Western Blotting
Epitope
C-Term
38
21
17
7
5
4
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
140
65
33
Host
Goat
115
30
5
3
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
116
60
42
29
22
7
4
3
2
2
1
1
Supplier
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Immunogen Peptidefrom C Terminus of the protein sequence according to NP_683708.1 Genename: TIRAP
Sequence C-EGEGERDSAT VSDL
Specificity This antibody detects TIRAP at C-Term.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name TIRAP (TIRAP Antibody Abstract)
Background Synonyms: Adaptor protein Wyatt, MAL, MyD88 adapter-like protein, TIR domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein
Gene ID 114609
NCBI Accession NP_683708
UniProt P58753
Research Area Immunology, Innate Immunity, Atherosclerosis
Pathways TLR Signaling
Application Notes Peptide ELISA: Limit dilution 1: 128000. Western Blot: 1-3 μg/mL. Approx 30 kDa band observed in Human Liver lysates (calculatedMW of 25.0 kDa according to NP_683708.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Supplier Images
 image for anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (C-Term) antibody (ABIN374117) anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (C-Term) antibody
Background publications Andreakos, Sacre, Smith et al.: "Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP." in: Blood, Vol. 103, Issue 6, pp. 2229-37, 2004 (PubMed).