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MTM1 antibody (Myotubularin 1) (C-Term)

Details for Product anti-MTM1 Antibody No. ABIN374119, Supplier: Log in to see
Antigen
  • wu:fb19c01
  • zgc:123266
  • CNM
  • MTMX
  • XLMTM
  • AF073996
  • Mtm
  • mKIAA4176
  • myotubularin 1
  • X-linked myotubular myopathy gene 1
  • MTM1
  • mtm1
  • Mtm1
Alternatives
anti-Human MTM1 antibody for ELISA
Epitope
C-Term
16
14
6
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human
77
49
24
4
3
2
2
2
2
1
1
Host
Goat
65
9
4
Clonality
Polyclonal
Conjugate
This MTM1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
57
33
15
13
11
3
2
1
1
1
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Immunogen eptide with sequence C-SSPSQMMPHVQTHF, from the C Terminus of the protein sequence Genename: MTM1
Specificity This antibody detects MTM1 at C-term.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Canine (Dog), Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name Myotubularin / MTM1 (MTM1 Antibody Abstract)
Background Dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. Could be involved in a signal transduction pathway necessary for late myogenesis, although its ubiquitous expression suggests a wider function.
Gene ID 4534
NCBI Accession NP_000243
UniProt Q13496
Pathways Inositol Metabolic Process
Application Notes Peptide ELISA: 1/16000. Western blot: 0.3 - 1 μg/mL. Approx 70 kDa band observed in lysates of Human SkeletalMuscle and of cell line HepG2 (calculated MW of 69.0 kDa according to NP_000243.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-MTM1 antibody (Myotubularin 1) (C-Term) (ABIN374119) anti-Myotubularin 1 (MTM1) (C-Term) antibody
 image for anti-MTM1 antibody (Myotubularin 1) (C-Term) (ABIN374119) anti-Myotubularin 1 (MTM1) (C-Term) antibody (Image 2)
Background publications Laporte, Hu, Kretz, Mandel, Kioschis, Coy, Klauck, Poustka, Dahl: "A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast." in: Nature genetics, Vol. 13, Issue 2, pp. 175-82, 1996 (PubMed).