TXNRD1 antibody (C-Term)

Catalog No. ABIN374236

This Goat Polyclonal antibody specifically detects TXNRD1 in WB. It exhibits reactivity toward Human and Pig.

Quick Overview for TXNRD1 antibody (C-Term) (ABIN374236)

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reactivity: Human, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNRD1 Antibody

Binding Specificity: C-Term

Sequence: TKRSGASILQ AGC

Specificity: This antibody detects Thioredoxin reductase 1 (TXNRD1) at C-term.

Cross-Reactivity (Details): Species reactivity (expected):PigSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_003321.2, NP_877393.1, NP_877419.1, NP_877420.1, NP_001087240.1. Genename: TXNRD1

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.1-1 μg/mL. Approx 60 kDa band observed in Human Placenta lysates(predicted MW of 50 kDa according to NP_003321).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: Thioredoxin Reductase 1 / TXNRD1

Background: Synonyms: GRIM-12, Gene associated with retinoid-IFN-induced mortality 12 protein, KDRF, KM-102-derived reductase-like factor, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase TR1

Gene ID: 7296

NCBI Accession: NP_003321

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis