DOK5 antibody (C-Term)

Catalog No. ABIN374474

Product Details anti-DOK5 Antibody

Target: DOK5 (Docking Protein 5 (DOK5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to Docking protein 5.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence CLHRTETFPAYRSEH, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL. Immunohistochemistry on paraffin sections: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5 (DOK5 Products)

Synonyms: C20orf180 antibody, 2700055C10Rik antibody, RGD1562846 antibody, docking protein 5 antibody, Docking protein 5 antibody, DOK5 antibody, dok5 antibody, Dok5 antibody

Background: DOK5 is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP. Two transcript variants encoding two different isoforms have been found for this gene.Synonyms: C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, IRS6, Insulin receptor substrate 6

Gene ID: 55816

NCBI Accession: NP_060901

UniProt: Q9P104