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HPGD antibody (C-Term)
HPGD
Reactivity: Human
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-HPGD Antibody
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Target
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HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Binding Specificity
All epitopes for HPGD antibodies
C-Term
Reactivity
All reactivities for HPGD antibodies
Human
Host
All hosts for HPGD antibodies
Goat
Clonality
All clonalities for HPGD antibodies
Polyclonal
Conjugate
All conjugates for HPGD antibodies
This HPGD antibody is un-conjugated
Application
All applications for HPGD antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to Prostaglandin dehydrogenase 1.
Purification
Affinity chromatography
Immunogen
Peptide with sequence C-DYDTTPFQAKTQ, from the C Terminus of the protein sequence
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Discover our top product HPGD Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HPGD
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Target
HPGD
(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))
Alternative Name
HPGD (HPGD Products )
Synonyms
CBR antibody, SDR21C1 antibody, hCBR1 antibody, 15-PGDH antibody, PGDH antibody, PGDH1 antibody, PHOAR1 antibody, SDR36C1 antibody, MGC80546 antibody, MGC79454 antibody, AV026552 antibody, carbonyl reductase 1 antibody, 15-hydroxyprostaglandin dehydrogenase antibody, hydroxyprostaglandin dehydrogenase 15-(NAD) antibody, 15-hydroxyprostaglandin dehydrogenase L homeolog antibody, hydroxyprostaglandin dehydrogenase 15 (NAD) antibody, CBR1 antibody, HPGD antibody, hpgd.L antibody, hpgd antibody, pgdh antibody, Hpgd antibody, PTRG_03214 antibody, VDBG_09957 antibody
Background
Prostaglandins are involved in many physiologic and cellular processes, such as inflammation. The NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) is the main enzyme of prostaglandin degradation. By catalyzing the conversion of the 15-hydroxyl group of prostaglandins into a keto group, this ubiquitous enzyme strongly reduces the biologic activity of these molecules. The induction of 15-PGDH expression by dexamethasone and other glucocorticoids at the therapeutic level provides an additional biochemical mechanism for the anti-inflammatory action of these glucocorticoids.Synonyms: 15-hydroxyprostaglandin dehydrogenase, PGDH, PGDH1, Prostaglandin dehydrogenase 1
Gene ID
3248
NCBI Accession
NP_000851
UniProt
P15428
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