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Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody

Details for Product No. ABIN374513, Supplier: Log in to see
Antigen
  • RP11-302K17.1
  • 5330434M19Rik
  • BLOC2
  • ru
  • Hsp6
Epitope
Internal Region
15
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
31
7
7
2
2
1
1
1
1
Host
Goat
16
14
1
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Western Blotting (WB)
29
19
8
2
1
Supplier
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Immunogen Peptide with sequence LRTELRDYRGLEC, from the internal region of the protein sequence
Specificity This antibody reacts to HPS6.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name HPS6 (HPS6 Antibody Abstract)
Background HPS6 has an intronless gene and may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in HPS6 gene are associated with Hermansky-Pudlak syndrome type 6.Synonyms: HPS-6, Hermansky-Pudlak syndrome 6 protein, Ru, Ruby-eye protein homolog
Gene ID 79803
NCBI Accession NP_079023
UniProt Q86YV9
Research Area Signaling
Application Notes Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody (ABIN374513) anti-Hermansky-Pudlak Syndrome 6 (HPS6) (Internal Region) antibody
Background publications Smeazzetto, Schröder, Thiel et al.: "Phospholamban generates cation selective ion channels." in: Physical chemistry chemical physics : PCCP, Vol. 13, Issue 28, pp. 12935-9, 2011 (PubMed).

Gautam, Chintala, Li et al.: "The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2)." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12935-42, 2004 (PubMed).