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Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody

Details for Product No. ABIN374540, Supplier: Log in to see
Antigen
  • CD32
  • CD32A
  • CDw32
  • FCG2
  • FCGR2
  • FCGR2A1
  • FcGR
  • IGFR2
  • CD32a
Epitope
C-Term
41
13
5
5
4
3
3
3
2
1
1
1
1
1
1
1
1
Reactivity
Human
120
7
7
5
3
2
2
Host
Goat
75
56
Clonality
Polyclonal
Conjugate
Un-conjugated
10
10
8
4
4
4
Application
Western Blotting (WB)
86
56
33
23
17
16
15
4
2
2
2
1
1
Supplier
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Immunogen Peptide with sequence C-PDALEEPDDQNRI, from the C Terminus of the protein sequence
Specificity This antibody reacts to CD32.
Purification Affinity chromatography
Alternative Name CD32 / FcRII-A (FCGR2A Antibody Abstract)
Background CD32 is a receptor for the Fc region of complexed or aggregated immunoglobulins gamma. This is a low affinity receptor. It is Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B cells. Binding to this receptor results in downmodulation of previous state of cell activation triggered via antigen receptors on B cells (BCR), T cells (TCR) or via another Fc receptor.Synonyms: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II
Gene ID 2212, 9606
UniProt P12318
Pathways
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody (ABIN374540) anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody
 image for anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody (ABIN374540) anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody (Image 2)
Background publications McGaha, Sorrentino, Ravetch: "Restoration of tolerance in lupus by targeted inhibitory receptor expression." in: Science (New York, N.Y.), Vol. 307, Issue 5709, pp. 590-3, 2005 (PubMed).