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Details for Product No. ABIN374540

Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibody

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Antigen
Synonyms CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN374540
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence C-PDALEEPDDQNRI, from the C Terminus of the protein sequence
Specificity This antibody reacts to CD32.
Purification Affinity chromatography
Alternative Name CD32 / FcRII-a
Background CD32 is a receptor for the Fc region of complexed or aggregated immunoglobulins gamma. This is a low affinity receptor. It is Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B cells. Binding to this receptor results in downmodulation of previous state of cell activation triggered via antigen receptors on B cells (BCR), T cells (TCR) or via another Fc receptor.
Alternate names: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II
Gene ID 2212
NCBI Accession 9606
UniProt P12318
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications McGaha, Sorrentino, Ravetch: "Restoration of tolerance in lupus by targeted inhibitory receptor expression." in: Science (New York, N.Y.), Vol. 307, Issue 5709, pp. 590-3, 2005 (PubMed).

Alternatives for antigen "Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A)", type "Antibodies"
Hosts (42), (38), (1)
Reactivities (76), (11), (5), (1), (1)
Applications (47), (29), (22), (18), (17), (10), (9), (6), (6), (1), (1), (1), (1)
Conjugates (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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