V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody

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Antigen
  • ERG
  • p55
  • erg-3
  • erg_E
  • D030036I24Rik
  • erg
  • erg_A
  • zgc:103429
  • v-ets erythroblastosis virus E26 oncogene like
  • potassium voltage-gated channel, subfamily H (eag-related), member 2
  • v-ets erythroblastosis virus E26 oncogene homolog (avian)
  • v-ets erythroblastosis virus E26 oncogene homolog
  • avian erythroblastosis virus E-26 (v-ets) oncogene related
  • v-ets avian erythroblastosis virus E26 oncogene
  • v-ets avian erythroblastosis virus E26 oncogene homolog
  • v-ets erythroblastosis virus E26 oncogene like (avian)
  • LOC100223535
  • KCNH2
  • ERG
  • erg-b
  • erg
  • Erg
  • erg-a
Epitope
C-Term
22
6
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
113
35
32
7
7
6
6
5
4
4
3
2
2
2
1
1
1
Host
Goat
58
36
19
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
74
55
42
41
36
20
10
6
2
1
1
1
1
Options
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Immunogen Peptide with sequence C-PNTRLPTSHMPSH, from the C Terminus of the protein sequence
Specificity This antibody reacts to ERG.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name ERG (ERG Antibody Abstract)
Background ERG (v-ets erythroblastosis virus E26 oncogene like isoform 2) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.Synonyms: Transcriptional regulator ERG, Transforming protein ERG
Gene ID 2078
NCBI Accession NP_001129626
UniProt P11308
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Hematopoietic Progenitors
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody (ABIN374642) anti-V-Ets erythroblastosis Virus E26 Oncogene Homolog (Avian) (ERG) (C-Term) antibody
Background publications Tomlins, Rhodes, Perner, Dhanasekaran, Mehra, Sun, Varambally, Cao, Tchinda, Kuefer, Lee, Montie, Shah, Pienta, Rubin, Chinnaiyan: "Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer." in: Science (New York, N.Y.), Vol. 310, Issue 5748, pp. 644-8, 2005 (PubMed).

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