Melanoma Gp100 (C-Term) antibody

Details for Product No. ABIN374704
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Antigen
Synonyms silverb
Epitope
C-Term
(7), (4), (3), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(16), (2)
Host
Goat
(14), (4), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(11), (9), (4), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN374704
357.50 $
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Immunogen Peptide with sequence CPIGENSPLLSGQQ, from the C Terminus of the protein sequence according to NP_008859.1
Specificity This antibody recognizes Silver homologue / Pmel17.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography
Background Melanoma gp100, a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.Synonyms: D12S53E, ME20-M, Melanocyte lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen, PMEL17, SILV, Silver locus protein homolog
Molecular Weight 70.3kDa (NP_008859.1).
Gene ID 6490
NCBI Accession NP_001186982
UniProt P40967
Research Area Cancer, Metabolism
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
anti-Melanoma Gp100 (C-Term) antibody anti-Melanoma Gp100 (C-Term) antibody
anti-Melanoma Gp100 (C-Term) antibody (2) anti-Melanoma Gp100 (C-Term) antibody (Image 2)
Background publications Fowler, Koulov, Alory-Jost et al.: "Functional amyloid formation within mammalian tissue." in: PLoS biology, Vol. 4, Issue 1, pp. e6, 2006 (PubMed).

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