Melanoma gp100 antibody (AA 25-467)

Catalog No. ABIN7159229

Product Details anti-Melanoma gp100 Antibody

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Binding Specificity: AA 25-467

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melanoma gp100 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Melanocyte protein PMEL protein (25-467AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Alternative Name: PMEL (PMEL Products)

Synonyms: D12S53E antibody, ME20 antibody, ME20-M antibody, ME20M antibody, P1 antibody, P100 antibody, PMEL17 antibody, SI antibody, SIL antibody, SILV antibody, gp100 antibody, D10H12S53E antibody, D12S53Eh antibody, Pmel17 antibody, Si antibody, Silv antibody, gp87 antibody, RPE1 antibody, MMP115 antibody, silverb antibody, silver antibody, cb397 antibody, fdv antibody, pmel17 antibody, sb:cb397 antibody, silva antibody, wu:fc11g11 antibody, wu:fj24g11 antibody, zgc:136622 antibody, premelanosome protein antibody, premelanosome protein b antibody, premelanosome protein a antibody, PMEL antibody, Pmel antibody, pmelb antibody, pmela antibody

Background:

Background: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Aliases: 95 kDa melanocyte specific secreted glycoprotein antibody, 95 kDa melanocyte-specific secreted glycoprotein antibody, D12S53E antibody, gp100 antibody, M-beta antibody, ME20 antibody, ME20 M/ME20 S antibody, ME20-M antibody, ME20-S antibody, ME20M antibody, ME20M/ME20S antibody, ME20S antibody, Melanocyte lineage specific antigen GP100 antibody, Melanocyte protein mel 17 antibody, Melanocyte protein Pmel 17 antibody, Melanocyte protein Pmel 17 precursor antibody, Melanocytes lineage-specific antigen GP100 antibody, Melanoma associated ME20 antigen antibody, Melanoma gp100 antibody, Melanoma-associated ME20 antigen antibody, Melanosomal matrix protein 17 antibody, Melanosomal matrix protein17 antibody, P1 antibody, p100 antibody, p26 antibody, PMEL 17 antibody, PMEL antibody, PMEL_HUMAN antibody, PMEL17 antibody, Premelanosome protein antibody, Secreted melanoma-associated ME20 antigen antibody, SI antibody, SIL antibody, SILV antibody, Silver (mouse homolog) like antibody, Silver homolog antibody, Silver locus protein homolog antibody, Silver, mouse, homolog of antibody

UniProt: P40967