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WT1 antibody (Wilms Tumor 1) (N-Term)

Details for Product anti-WT1 Antibody No. ABIN374714, Supplier: Log in to see
Antigen
  • AWT1
  • CWT1
  • D630046I19Rik
  • EWS-WT1
  • GUD
  • gud
  • NPHS4
  • si:ch211-160j6.3
  • wagr
  • WAGR
  • WIT-2
  • wit-2
  • WT
  • wt-1
  • Wt-1
  • WT-1
  • wt1
  • WT1
  • WT33
  • wt33
  • XeWT1
  • xWT1
  • xwt1
  • XWT1a
  • XWT1b
  • zgc:152697
Epitope
N-Term
37
19
15
15
14
12
9
9
9
5
4
2
1
1
1
1
1
1
1
Reactivity
Human
222
49
31
2
1
1
1
1
1
Host
Goat
113
96
14
Clonality
Polyclonal
Conjugate
This WT1 antibody is un-conjugated
9
9
8
7
5
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
Application
Western Blotting (WB)
122
104
99
59
58
52
28
4
4
2
2
1
1
Supplier
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Immunogen Peptide with sequence QDPASTCVPEPASQH, from the N Terminus of the protein sequence
Specificity This antibody reacts to Wilms tumor 1. This antibody is expected to recognise all four reported isoforms.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name WT1 / Wilms Tumor Protein (WT1 Antibody Abstract)
Background WT1 encodes multiple isoforms of a zinc finger transcription factor essential for correct mammalian urogenital development. Different WT1 isoforms are thought to regulate transcription and participate in mRNA processing, functions reflected by a complex sub nuclear distribution. In humans, the preservation of the correct isoform ratio and their localization has been reported to be vital, and its disruption to result in disease. This gene has been reported as a useful marker for several types of illnesses. Mutations in this gene lead to the development of Wilm's Tumor, a sporadic and familial childhood kidney tumor.Synonyms: WT33
Gene ID 7490, 9606
UniProt P19544
Application Notes ELISA: 1/4000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3, 0.02 % sodium azide, 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-WT1 antibody (Wilms Tumor 1) (N-Term) (ABIN374714) anti-Wilms Tumor 1 (WT1) (N-Term) antibody
Background publications Rao, Pham, Imam, MacLean, Murali, Furuta, Sinha-Hikim, Wilkinson: "Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis." in: Genes & development, Vol. 20, Issue 2, pp. 147-52, 2006 (PubMed).