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Cholinergic Receptor, Muscarinic 1 (CHRM1) antibody

Antigen

Cholinergic Receptor, Muscarinic 1 (CHRM1)
Synonyms M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517
Clonality Polyclonal
Host
Reactivity
Alternatives

Dog (Canine)
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN374726
Quantity 0.1 mg  (0.5 mg/ml)
Price 290.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics Synonyms: CHRM1, mAChR M1, mAChR-M1
Alternative name Muscarinic acetylcholine receptor M1
Swiss-Prot P11229
Immunogen Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the proteinsequence
Cross-Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Description The muscarinic cholinergic receptors belong to a larger family of G protein-coupledreceptors. The functional diversity of these receptors is defined by the binding ofacetylcholine and includes cellular responses such as adenylate cyclase inhibition,phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptorsinfluence many effects of acetylcholine in the central and peripheral nervous system. Themuscarinic cholinergic receptor 1 is involved in mediation of vagally-inducedbronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinicreceptors are so called as they are more sensitive to the effects of the alkaloid muscarine,rather than nicotine.
Specificity This antibody reacts to M1 mAChR / CHRM1. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Aff - Purified
Buffer Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Neurotransmitters, Hormones, Receptors
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Cholinergic Receptor, Muscarinic 1 (CHRM1)", type "Antibodies"
Hosts Rabbit (4), Goat (2)
Reactivities Human (4), Mouse (Murine) (3), Rat (Rattus) (3), Dog (Canine) (1)
Applications Western Blotting (WB) (6), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)