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CCM2 antibody (Cerebral Cavernous Malformation 2) (Internal Region)

Details for Product anti-CCM2 Antibody No. ABIN374751, Supplier: Login to see New
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Synonyms malcavernin, CCM2, C7orf22, OSM, BC029157
Internal Region
(12), (5), (2), (2), (1), (1), (1)
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(59), (8), (8), (2), (2), (1), (1), (1), (1), (1)
(32), (15), (12)
This CCM2 antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(53), (26), (14), (8), (3), (2)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence C-KGEKSRDKKAHEK, from the internal region of the protein sequence
Specificity This antibody reacts to Malcavernin.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name Malcavernin (CCM2 Antibody Abstract)
Background CCM2 may function as a scaffold protein for MAP2K3-MAP3K3 signaling. It seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.Synonyms: C7orf22, CCM2, Cerebral cavernous malformations 2 protein, PP10187
Gene ID 83605, 9606
UniProt Q9BSQ5
Application Notes Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody in aliquots at -20 °C.
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 image for anti-CCM2 antibody (Cerebral Cavernous Malformation 2) (Internal Region) (ABIN374751) anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Background publications Zawistowski, Stalheim, Uhlik et al.: "CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis." in: Human molecular genetics, Vol. 14, Issue 17, pp. 2521-31, 2005 (PubMed).

Catalog No. ABIN374751
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