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Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody

Details for Product No. ABIN374756, Supplier: Login to see
Antigen
  • clic4
  • MGC89006
  • MGC79614
  • CLIC4
  • DKFZp459A0325
  • xclic4
  • CLIC4L
  • H1
  • MTCLIC
  • huH1
  • p64H1
  • cb142
  • wu:fb33c05
  • wu:fc30h10
  • D0Jmb3
  • TU-74
  • mc3s5
  • mtCLIC
Epitope
N-Term
26
15
7
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
90
52
48
5
2
1
1
1
1
1
1
1
Host
Goat
79
19
5
Clonality
Polyclonal
Conjugate
Un-conjugated
8
5
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
77
53
34
24
18
11
6
3
3
1
Supplier
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Immunogen Peptide with sequence NGLKEEDKEPLIE-C, from the N Terminus of the protein sequence
Specificity This antibody reacts to CLIC4.
Cross-Reactivity (Details) Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, Mouse.
Purification Affinity chromatography
Alternative Name CLIC4 (CLIC4 Antibody Abstract)
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) (from Entrez Gene). CLIC4 is thought to play a role in apoptosis and has been shown to translocate to the nucleus under stress conditions.Synonyms: Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, mc3s5, mtCLIC, p64H1
Gene ID 25932
NCBI Accession NP_039234
UniProt Q9Y696
Research Area Signaling, Metabolism, Cell Cycle, Apoptosis/Necrosis
Pathways
Application Notes Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL. Immunofluorescence: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody (ABIN374756) anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody
 image for anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody (ABIN374756) anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody (Image 2)
Background publications Suh, Crutchley, Koochek et al.: "Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 1, pp. 121-31, 2007 (PubMed).