Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody

Details for Product No. ABIN374756
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Antigen
Synonyms clic4, MGC89006, MGC79614, CLIC4, DKFZp459A0325, xclic4, CLIC4L, H1, MTCLIC, huH1, p64H1, cb142, wu:fb33c05, wu:fc30h10, D0Jmb3, TU-74, mc3s5, mtCLIC
Epitope
N-Term
(15), (6), (2), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(51), (34), (33), (15), (12), (11), (11), (1), (1), (1)
Host
Goat
(52), (6), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(49), (36), (22), (18), (9), (8), (6), (5), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN374756
357.50 $
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Immunogen Peptide with sequence NGLKEEDKEPLIE-C, from the N Terminus of the protein sequence
Specificity This antibody reacts to CLIC4. Species Reactivity: Tested: Human, Mouse. Expected from sequence similarity: Rat, Canine.
Purification Affinity chromatography
Alternative Name CLIC4
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family, the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells) (from Entrez Gene). CLIC4 is thought to play a role in apoptosis and has been shown to translocate to the nucleus under stress conditions.
Alternate names: Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, mc3s5, mtCLIC, p64H1
Gene ID 25932
NCBI Accession NP_039234
UniProt Q9Y696
Research Area Signaling, Metabolism, Cell Cycle, Apoptosis/Necrosis
Application Notes Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 µg/ml. Immunofluorescence: 5µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody (2) anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibody (Image 2)
Background publications Suh, Crutchley, Koochek et al.: "Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 1, pp. 121-31, 2007 (PubMed).

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