DPP4 antibody (Internal Region)

Catalog No. ABIN374762

There is 1 publication for this product available. The Goat Polyclonal anti-DPP4 antibody is suitable to detect DPP4 in samples from Human, Rat, Mouse and Dog. It has been validated for WB and EIA.

Quick Overview for DPP4 antibody (Internal Region) (ABIN374762)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-DPP4 Antibody

Binding Specificity: Internal Region

Sequence: C-PPHFDKSKKY P

Specificity: This antibody recognizes CD26 / DPP4.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Canine.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001926.2 Genename: DPP4

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-DPP4 antibody (ABIN374762)

Antel, Freedman, Brodovsky, Francis, Duquette: "Activated suppressor cell function in severely disabled patients with multiple sclerosis." in: Annals of neurology, Vol. 25, Issue 2, pp. 204-7, (1989) (PubMed).

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26 / DPP4

Background: CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein] is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103

Gene ID: 1803, 9606

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity