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Glucose-6-Phosphate Dehydrogenase antibody (G6PD) (AA 308-320)

Details for Product anti-G6PD Antibody No. ABIN374790, Supplier: Log in to see
Antigen
  • BA3433
  • CORTRD1
  • Dsim\\\\G6pd
  • Dsim\\\\G6pdh
  • Dsim\\\\GD24877
  • dsim_GLEANR_8868
  • fj78b06
  • G-6PD
  • g6pd
  • G6PD
  • G6pd
  • G6PD1
  • g6pd2
  • G6PDH
  • g6pdh
  • G6pdx
  • G6pdx-ps1
  • GD24877
  • GDH
  • Gpd-2
  • Gpd2
  • PSPTO1300
  • PSPTO3121
  • si:dkey-90a13.8
  • wu:fj78b06
  • Zw
Epitope
AA 308-320, Internal Region
27
25
12
8
8
7
7
6
5
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
177
52
50
21
10
8
6
3
3
2
2
2
2
Host
Goat
117
56
51
Clonality
Polyclonal
Conjugate
This Glucose-6-Phosphate Dehydrogenase antibody is un-conjugated
23
9
8
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
182
127
61
40
38
36
24
23
16
12
10
6
5
5
4
Supplier
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Immunogen Synthetic Peptide from the internal region (aa 308-320) of Human G6PD. Genename: G6PD
Sequence C-STNSDDVRDE KVK
Specificity This antibody is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat and Dog (Canine).
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography.
Alternative Name G6PD (G6PD Antibody Abstract)
Background Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency, one benefit of having G6PD deficiency is that it confers a resistance to malaria.Synonyms: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase
Gene ID 2539, 9606
UniProt P11413
Application Notes Peptide ELISA: Limit dilution: 1/32000. Western Blot: Use at 0.03-0.1 μg/mL. Detects a double band of approx. 55-60 kDa band in HumanTestis, Thyroid and Tonsil lysates. Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Testis shows strongcytoplasm staining in spermatogonia.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Glucose-6-Phosphate Dehydrogenase antibody (G6PD) (AA 308-320) (ABIN374790) anti-Glucose-6-Phosphate Dehydrogenase (G6PD) (AA 308-320), (Internal Region) antibody
 image for anti-Glucose-6-Phosphate Dehydrogenase antibody (G6PD) (AA 308-320) (ABIN374790) anti-Glucose-6-Phosphate Dehydrogenase (G6PD) (AA 308-320), (Internal Region) antibody (Image 2)
 image for anti-Glucose-6-Phosphate Dehydrogenase antibody (G6PD) (AA 308-320) (ABIN374790) anti-Glucose-6-Phosphate Dehydrogenase (G6PD) (AA 308-320), (Internal Region) antibody (Image 3)
Background publications Guindo, Fairhurst, Doumbo, Wellems, Diallo: "X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria." in: PLoS medicine, Vol. 4, Issue 3, pp. e66, 2007 (PubMed).