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IGF2BP2 antibody (Insulin-Like Growth Factor 2 MRNA Binding Protein 2) (C-Term)

Details for Product anti-IGF2BP2 Antibody No. ABIN374940, Supplier: Log in to see
Antigen
  • C330012H03Rik
  • IMP-2
  • IMP2
  • Imp2
  • Neilsen
  • p62
  • RGD1305614
  • VICKZ2
Epitope
C-Term
29
16
7
7
5
5
4
2
2
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine)
117
31
24
10
8
2
1
1
1
1
1
Host
Goat
76
32
14
Clonality
Polyclonal
Conjugate
This IGF2BP2 antibody is un-conjugated
7
6
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
97
54
35
33
27
12
11
7
4
2
1
Supplier
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Immunogen Peptide with sequence C-KQQEQKYPQGVASQR, from the C Terminus of the protein sequence
Specificity This antibody is expected to recognise both reported isoforms of IGF2BP2 (NP_006539.3 and NP_001007226.1).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name IGF2BP2 (IGF2BP2 Antibody Abstract)
Background IGF2BP2 is a member of the IGF-II mRNA binding protein (IMP) family. It contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, IMP2, Insulin-like growth factor 2 mRNA-binding protein 2, VICKZ family member 2, VICKZ2
Gene ID 10644, 9606
UniProt Q9Y6M1
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-IGF2BP2 antibody (Insulin-Like Growth Factor 2 MRNA Binding Protein 2) (C-Term) (ABIN374940) anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody
 image for anti-IGF2BP2 antibody (Insulin-Like Growth Factor 2 MRNA Binding Protein 2) (C-Term) (ABIN374940) anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (Image 2)
Background publications Zeggini, Weedon, Lindgren, Frayling, Elliott, Lango, Timpson, Perry, Rayner, Freathy, Barrett, Shields, Morris, Ellard, Groves, Harries, Marchini, Owen, Knight, Cardon, Walker, Hitman, Morris, Doney et al.: "Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. ..." in: Science (New York, N.Y.), Vol. 316, Issue 5829, pp. 1336-41, 2007 (PubMed).