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LASS1 antibody (Internal Region)
CERS1
Reactivity: Human, Mouse, Rat, Cow
WB
Host: Goat
Polyclonal
unconjugated
Product Details anti-LASS1 Antibody
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Target
See all LASS1 (CERS1) Antibodies
LASS1 (CERS1)
(Ceramide Synthase 1 (CERS1))
Binding Specificity
All epitopes for LASS1 antibodies
Internal Region
Reactivity
All reactivities for LASS1 antibodies
Human, Mouse, Rat, Cow
Host
All hosts for LASS1 antibodies
Goat
Clonality
All clonalities for LASS1 antibodies
Polyclonal
Conjugate
All conjugates for LASS1 antibodies
This LASS1 antibody is un-conjugated
Application
All applications for LASS1 antibodies
Western Blotting (WB)
Specificity
This antibody is expected to recognize both reported isoforms of LASS1 (NP_067090.1, NP_937850.1)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rat, Bovine. Species reactivity (tested):Human.
Purification
Affinity chromatography
Immunogen
Peptide with sequence C-KDLREYDTAEAQ, from the internal region of the protein sequence
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Alternatives
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Application Details
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Application Notes
Peptide ELISA: 1/64000. Western Blot: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for LASS1
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Target
LASS1 (CERS1)
(Ceramide Synthase 1 (CERS1))
Alternative Name
LASS1 (CERS1 Products )
Synonyms
LAG1 antibody, LASS1 antibody, UOG1 antibody, Lass1 antibody, Uog-1 antibody, to antibody, LAG1 HOMOLOG 1 antibody, LONGEVITY ASSURANCE GENE 1 antibody, ceramide synthase 1 antibody, TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein antibody, CERS1 antibody, Cers1 antibody, LAG1 antibody
Background
LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing mainly one fatty acid donnor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.Synonyms: LAG1, LAG1 longevity assurance homolog 1, LASS1, Longevity assurance gene 1 protein homolog 1, UOG1
Gene ID
10715, 9606
UniProt
P27544
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