IMPDH2 antibody (Internal Region)

Catalog No. ABIN375045

The Goat Polyclonal anti-IMPDH2 antibody (ABIN375045) specifically detects IMPDH2 in WB. The antibody is reactive with Human samples.

Quick Overview for IMPDH2 antibody (Internal Region) (ABIN375045)

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IMPDH2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IMPDH2 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to IMPDH2.

Purification: Affinity chromatography

Immunogen: Peptide with sequence KEEEHDCFLEEI, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IMPDH2

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Alternative Name: IMPDH2

Background: Inosine monophosphate dehydrogenase (IMPDH) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis. It converts inosine 5'-monophosphate to xanthine 5'-monophosphate using NAD as a cofactor. IMPDH has been shown to play a significant role in the growth and malignancy of some tumors as guanine nucleotide Synonyms: EC=1.1.1.205, IMP dehydrogenase 2, IMPD-2, IMPD2, IMPDH-II, Inosine-5'-monophosphate dehydrogenase 2

Gene ID: 3615, 9606

UniProt: P12268

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome