NOVA1 antibody (Internal Region)

Catalog No. ABIN375110

Product Details anti-NOVA1 Antibody

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NOVA1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to NOVA1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-REMPQNVAKTEPVS, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NOVA1

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Alternative Name: NOVA1 (NOVA1 Products)

Synonyms: Nova-1 antibody, NOVA1 antibody, si:ch211-222c22.9 antibody, 9430099M15Rik antibody, G630039L02 antibody, NOVA alternative splicing regulator 1 antibody, neuro-oncological ventral antigen 1 L homeolog antibody, neuro-oncological ventral antigen 1 antibody, RNA-binding protein Nova-1 antibody, lipid A export ATP-binding/permease protein antibody, NOVA1 antibody, Nova1 antibody, nova1.L antibody, nova1 antibody, LOC790874 antibody, novA1 antibody

Background: Nova proteins are splicing factors that are expressed specifically in the central nervous system, where they regulate a large number of pre-mRNAs encoding synaptic proteins. Nova1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer.Synonyms: Neuro-oncological ventral antigen 1, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA-binding protein Nova-1, Ventral neuron-specific protein 1

Gene ID: 4857, 9606

UniProt: P51513