The antibody detects: Human MMP-9 Does not cross react to human MMP-1, MMP-2 or MMP-3 To insure lot-to-lot consistency, each batch of product is tested by ELISA to conform with the characteristics of a standard reference reagent.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume
1 mL
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Protect conjugated products from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage
4 °C
Target
MMP 9 (MMP9)
(Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to brea kDaown connective tissue. MMP-9 is also known as gelatinase B and 92 kDa gelatinase. MMP-9, along with MMP-2, belongs to the gelatinase group of MMP's which have three repeats of a type II fibronectin domain inserted in the catalytic domain. MMP-9 has shown direct and indirect substrate specificity to collagens IV, V, X and XIV, gelatin, elastin, proteoglycans, plasminogen, aggrecan, galectin-3, entactin, fibrillin, fibrin, IL-1 β, amyloid β peptide and myelin basic protein.