C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (N-Term), (C-Term) antibody

Details for Product No. ABIN387760
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Antigen
Synonyms VEGFD, VEGF-D, Vegfd, AI325264, Vegf-d, FIGF, vegfd, vegf-d
Epitope
N-Term, C-Term
(8), (7), (6), (5), (3), (3), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(65), (31), (28), (13), (12), (12), (12), (6), (1)
Host
Mouse
(67), (10), (3), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(68), (34), (18), (15), (10), (7), (6), (5), (4), (4), (1)
Pubmed 5 references available
Catalog no. ABIN387760
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.
Clone 28AT743-288-48
Isotype IgG1
Specificity This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name VEGF4
Background The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
Synonyms: Vascular Endothelial Growth Factor D, c-fos-induced growth factor, FIGF, VEGFD, VEGF-D, VEGF4
Molecular Weight 40444 DA
Gene ID 2277
UniProt O43915
Research Area Cell Signaling, Cell Structure, Cancer, Cell Cycle
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) (N-Term), (C-Term) antibody The anti-VEGF4 Mab (ABIN387760) is used in Western blot to detect VEGF4 in HDMEC cell lysate.
Background publications Becker, Pavlakovic, Ludewig et al.: "Neuroblastoma progression correlates with downregulation of the lymphangiogenesis inhibitor sVEGFR-2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 5, pp. 1431-41, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Romero, Velez Edwards, Kusanovic et al.: "Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes." in: American journal of obstetrics and gynecology, Vol. 202, Issue 5, pp. 431.e1-34, 2010 (PubMed).

Deguchi, Ichikawa, Soga et al.: "Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer." in: Anticancer research, Vol. 30, Issue 6, pp. 2361-6, 2010 (PubMed).

Romero, Friel, Velez Edwards et al.: "A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)." in: American journal of obstetrics and gynecology, Vol. 203, Issue 4, pp. 361.e1-361.e30, 2010 (PubMed).

Hosts (67), (10), (3), (2)
Reactivities (65), (31), (28), (13), (12), (12), (12), (6), (1)
Applications (68), (34), (18), (15), (10), (7), (6), (5), (4), (4), (1)
Conjugates (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (6), (5), (3), (3), (1), (1), (1)
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