SOD2 antibody

Catalog No. ABIN387807

Cited in 1 publication. The Mouse Monoclonal anti-SOD2 antibody (Clone 37CT127-5-11-6) (ABIN387807) specifically detects SOD2 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SOD2 antibody (ABIN387807)

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 37CT127-5-11-6

Product Details anti-SOD2 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged SOD protein(Fragment) was used to produced this monoclonal antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SOD2 antibody (ABIN387807)

Bertolo, Capossela, Fränkl, Baur, Pötzel, Stoyanov: "Oxidative status predicts quality in human mesenchymal stem cells." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 3, (2017) (PubMed).

Target Details for SOD2

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Alternative Name: SOD2

Background: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 24750

Gene ID: 6648

NCBI Accession: NP_000627, NP_001019636, NP_001019637

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling