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Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 527-559), (N-Term) antibody

Details for Product No. ABIN387900, Supplier: Log in to see
Antigen
  • JMJD2A
  • JHDM3A
  • JMJD2
  • TDRD14A
  • D4Ertd222e
  • Jmjd2
  • Jmjd2a
  • mKIAA0677
Epitope
AA 527-559, N-Term
12
11
8
5
4
4
4
2
2
1
1
1
1
1
Reactivity
Human
75
24
15
2
Host
Rabbit
57
18
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
1
1
1
1
Application
Western Blotting (WB)
51
38
22
19
16
14
11
4
2
2
2
1
1
Supplier
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Immunogen This JMJD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-559 AA from the N-terminal region of human JMJD2A.
Clone RB10787
Isotype Ig
Specificity This JMJD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536~565 amino acids from the N-terminal region of human JMJD2A.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name JMJD2A (KDM4A Antibody Abstract)
Background JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Synonyms: JMJD2A, JHDM3A, JMJD2, KIAA0677
Molecular Weight 120720 DA
Gene ID 9682
NCBI Accession NP_055478
Research Area Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 527-559), (N-Term) antibody (ABIN387900) Western blot analysis of JMJD2A(arrow) using rabbit polyclonal JMJD2A (N-term)(ABIN38...
Background publications Gray, Iglesias, Lizcano et al.: "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein." in: The Journal of biological chemistry, Vol. 280, Issue 31, pp. 28507-18, 2005 (PubMed).