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KDM4A Products

(Lysine (K)-Specific Demethylase 4A (KDM4A))
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009].

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Featured KDM4A Categories

KDM4A Antibodies

High quality antibodies with extensive validation data.

KDM4A ELISA Kits

Reliable ELISA kits for a wide range of species.

KDM4A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KDM4A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7441397
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542632
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC
Validations
  • (4)
  • (3)
Cat. No. ABIN969230
Quantity 100 μL
Datasheet Datasheet

Recommended KDM4A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957575
Quantity 96 tests
Datasheet Datasheet

Recommended KDM4A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123808
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093348
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136288
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KDM4A products

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Carbonneau, M Gagné, Lalonde, Germain, Motorina, Guiot, Secco, Vincent, Tumber, Hulea, Bergeman, Oppermann, Jones, Laplante, Topisirovic, Petrecca, Huot, Mallette: "The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway." in: Nature communications, Vol. 7, pp. 12700, (2016) (PubMed).

Gibbs-Seymour, Markiewicz, Bekker-Jensen, Mailand, Hutchison: "Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage." in: Aging cell, Vol. 14, Issue 2, pp. 162-9, (2015) (PubMed).

Qiu, Fan, Zhu, Kwan, Chen, Chen, Ying, Zhou, Gu, Wang, Cheng, Zeng, Wan, Mok, Wong, Bao: "KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1." in: Oncotarget, Vol. 6, Issue 31, pp. 31702-20, (2015) (PubMed).

Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).

Das, Chai, Jung, Das, Kang, Lee, Seo, Chai: "JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cells." in: Experimental cell research, Vol. 328, Issue 2, pp. 361-78, (2014) (PubMed).

Dikopoltsev, Foltyn, Zehl, Jensen, Mori, Radzishevsky, Wolosker: "FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33904-15, (2014) (PubMed).

Hosseinzadeh Shirzeily, Pasbakhsh, Amidi, Mehrannia, Sobhani: "Comparison of differentiation potential of male mouse adipose tissue and bone marrow derived-mesenchymal stem cells into germ cells." in: Iranian journal of reproductive medicine, Vol. 11, Issue 12, pp. 965-76, (2014) (PubMed).

Young, McDonald, Hendzel: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).

Kim, Shin, Berry, Oh, Janknecht: "The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells." in: Journal of cellular biochemistry, Vol. 113, Issue 4, pp. 1368-76, (2012) (PubMed).

Synonyms and alternative names related to KDM4A

lysine demethylase 4A (KDM4A), lysine-specific demethylase 4A (LOC100228023), lysine (K)-specific demethylase 4A (KDM4A), lysine (K)-specific demethylase 4A (Kdm4a), lysine demethylase 4A (Kdm4a), D4Ertd222e, JHDM3A, JMJD2, Jmjd2, JMJD2A, Jmjd2a, mKIAA0677, TDRD14A

Protein level used designations for KDM4A

  • jumonji domain containing 2A
  • lysine (K)-specific demethylase 4A
  • lysine-specific demethylase 4A
  • jumonji domain-containing protein 2A
  • JmjC domain-containing histone demethylation protein 3A
  • jumonji domain-containing 2A
  • lysine-specific demethylase 4A-like
  • jmjC domain-containing histone demethylation protein 3A
  • jumonji C domain-containing histone demethylase 3A
  • jumonji domain containing 2
  • tudor domain containing 14A
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