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SENP2 antibody (C-Term)

SENP2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB2705 unconjugated
Catalog No. ABIN388045
  • Target See all SENP2 Antibodies
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Binding Specificity
    • 15
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 502-533, C-Term
    Reactivity
    • 38
    • 31
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 47
    • 7
    Rabbit
    Clonality
    • 47
    • 7
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SENP2 antibody is un-conjugated
    Application
    • 44
    • 19
    • 17
    • 13
    • 13
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.
    Clone
    RB2705
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SENP2 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Maruyama, Lin, Chiu, Yu, Porter, Hsu: "Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development." in: Scientific reports, Vol. 6, pp. 20999, (2016) (PubMed).

    La Salle, Sun, Zhang, Matunis, Handel: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).

  • Target
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    Alternative Name
    SENP2 (SENP2 Products)
    Synonyms
    2310007L05Rik antibody, 4930538C18Rik antibody, AI646780 antibody, AW554757 antibody, Smt3ip2 antibody, SuPr-1 antibody, mKIAA1331 antibody, AXAM2 antibody, SMT3IP2 antibody, Axam antibody, SUMO/sentrin specific peptidase 2 antibody, SUMO1/sentrin/SMT3 specific peptidase 2 antibody, Sumo1/sentrin/SMT3 specific peptidase 2 antibody, Senp2 antibody, SENP2 antibody
    Background
    SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
    Molecular Weight
    67855
    Gene ID
    59343
    NCBI Accession
    NP_067640
    UniProt
    Q9HC62
    Pathways
    Chromatin Binding
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