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Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (AA 458-487), (C-Term) antibody

Details for Product No. ABIN388154, Supplier: Log in to see
Antigen
  • id:ibd2914
  • nstm
  • wu:fb38a04
  • wu:fc55d07
  • zgc:123093
  • e2ig3
  • C77032
  • E2IG3
  • NNP47
  • NS
  • BC037996
  • Ns
Epitope
AA 458-487, C-Term
28
17
8
6
6
6
5
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
81
40
16
1
1
Host
Rabbit
75
19
4
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
83
51
11
9
9
8
4
4
2
1
1
1
1
1
Supplier
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Immunogen This Nucleostemin (GNL3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 AA from the C-terminal region of human Nucleostemin (GNL3).
Clone RB13446
Isotype Ig
Specificity This GNL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465~495 amino acids from the C-term region of human GNL3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Nucleostemin (GNL3) (E2IG3 Antibody Abstract)
Background GNL3 is found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells, and may be required to maintain the proliferative capacity of stem cells.
Synonyms: Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, E2IG3, NS
Molecular Weight 61997 DA
Gene ID 26354
UniProt Q9BVP2
Research Area Stem Cells, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (AA 458-487), (C-Term) antibody (ABIN388154) Western blot analysis of GNL3 Antibody (C-term) (ABIN388154) in HL60 cell line lysate...
Immunohistochemistry (IHC) image for anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) (AA 458-487), (C-Term) antibody (ABIN388154) Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GNL3 a...
Background publications Ma, Pederson: "Depletion of the nucleolar protein nucleostemin causes G1 cell cycle arrest via the p53 pathway." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2630-5, 2007 (PubMed).