Cadherin 5 antibody (CDH5) (AA 106-134)

Details for Product anti-CDH5 Antibody No. ABIN389186, Supplier: Log in to see
Antigen
  • 7B4
  • AA408225
  • Cd144
  • VE-Cad
  • VECD
  • VEcad
  • Vec
  • wu:fc88a07
  • CD144
  • cadherin-5
  • cadherin 5, type 2 (vascular endothelium)
  • cadherin 5
  • CDH5
  • Cdh5
  • cdh5
Alternatives
anti-Human Cadherin 5 antibody for Blocking Antibody
Epitope
AA 106-134, N-Term
17
16
16
12
10
9
9
8
8
7
6
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
226
162
45
5
4
2
2
1
1
1
1
1
Host
Rabbit
129
122
86
2
Clonality (Clone)
Polyclonal ()
Conjugate
This Cadherin 5 antibody is un-conjugated
27
16
15
14
11
7
7
7
6
6
5
5
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
196
191
90
80
52
42
20
17
14
14
13
10
7
7
6
6
6
4
4
3
3
3
3
2
2
2
1
1
1
1
Options
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Immunogen This VE Cadherin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 AA from the N-terminal region of human VE Cadherin.
Clone RB13659
Isotype Ig
Specificity This CDH5 (N-term) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113~142 amino acids from the N-term of human CDH5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VE Cadherin (CDH5) (CDH5 Antibody Abstract)
Background CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Synonyms: Cadherin-5,Vascular endothelial cadherin,VE-cadherin,7B4 antigen,CD144 antigen,CDH5
Molecular Weight 87516 DA
Gene ID 1003
UniProt P33151
Research Area Cell Structure, Cancer
Pathways Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Cadherin 5 antibody (CDH5) (AA 106-134) (ABIN389186) Western blot analysis of anti-CDH5 Pab (ABIN389186) in 293 cell line lysates (35 µg/l...
Immunohistochemistry (IHC) image for anti-Cadherin 5 antibody (CDH5) (AA 106-134) (ABIN389186) Flow cytometric analysis of 293 cells using VE Cadherin Antibody (CDH5) (N-term)(bott...
Background publications Breviario, Caveda, Corada, Martin-Padura, Navarro, Golay, Introna, Gulino, Lampugnani, Dejana: "Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 15, Issue 8, pp. 1229-39, 1995 (PubMed).