LECT1 antibody (C-Term)

Catalog No. ABIN389196

Product Details anti-LECT1 Antibody

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Binding Specificity: AA 253-281, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LECT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M, Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the C-terminal region of human LECT1.

Clone: RB15073

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Alternative Name: LECT1 (LECT1 Products)

Synonyms: chm1 antibody, chm-i antibody, bricd3 antibody, MGC53801 antibody, MGC82444 antibody, chondromodulin-I antibody, Lect1 antibody, BRICD3 antibody, CHM-I antibody, CHM1 antibody, MYETS1 antibody, Bricd3 antibody, ChM-I antibody, Chm-1 antibody, chondromodulin L homeolog antibody, leukocyte cell derived chemotaxin 1 antibody, chondromodulin antibody, cnmd.L antibody, lect1 antibody, CNMD antibody, cnmd antibody, Cnmd antibody

Background: LECT1 a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.

Molecular Weight: 37102

Gene ID: 11061

NCBI Accession: NP_001011705, NP_008946

UniProt: O75829