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LGR5 antibody (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5) (AA 605-638)

Details for Product anti-LGR5 Antibody No. ABIN389217, Supplier: Login to see
Antigen
  • lgr5-a
  • lgr5a
  • FEX
  • Gpr49
  • GPR49
  • GPR67
  • GRP49
  • HG38
Epitope
AA 605-638, Loop 1
21
10
8
5
5
5
5
4
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
118
31
6
Host
Rabbit
73
46
2
Clonality (Clone)
Polyclonal ()
Conjugate
This LGR5 antibody is un-conjugated
2
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
76
52
36
29
27
17
17
3
3
2
2
2
1
1
Supplier
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Immunogen This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-638 AA from human LGR5.
Clone RB14210
Isotype Ig
Specificity This LGR5 (GPR49) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614~644 amino acids from the loop1 region of human LGR5.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name LGR5 (GPR49) (LGR5 Antibody Abstract)
Background LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.
Synonyms: Leucine-rich repeat-containing G-protein coupled receptor 5 [Precursor], Orphan G-protein coupled receptor HG38, G-protein coupled receptor 49, G-protein coupled receptor 67, LGR5, GPR49, GPR67
Molecular Weight 99867 DA
Gene ID 8549
UniProt O75473
Research Area Cell Signaling, Stem Cells, Cell Cycle, Cell Structure
Pathways
Application Notes IHC (p) = 1:10-50, WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-LGR5 antibody (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5) (AA 605-638) (ABIN389217) Formalin-fixed and paraffin-embedded human brain tissue reacted with LGR5/GPR49 antib...
Western Blotting (WB) image for anti-LGR5 antibody (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5) (AA 605-638) (ABIN389217) LGR5/GPR49 Antibody (loop1) (ABIN389217) western blot analysis in HL-60 cell line lys...
Background publications Barker, van Es, Kuipers et al.: "Identification of stem cells in small intestine and colon by marker gene Lgr5." in: Nature, Vol. 449, Issue 7165, pp. 1003-7, 2007 (PubMed).