ADCY2 antibody (C-Term)

Catalog No. ABIN389223

The Rabbit Polyclonal anti-ADCY2 antibody (Clone RB14942) (ABIN389223) specifically detects ADCY2 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ADCY2 antibody (C-Term) (ABIN389223)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14942

Product Details anti-ADCY2 Antibody

Binding Specificity: AA 940-969, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-969 amino acids from the C-terminal region of human ADCY2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: ADCY2

Background: ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Molecular Weight: 123603

Gene ID: 108

NCBI Accession: NP_065433

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma