TUFM antibody (N-Term)

Catalog No. ABIN389459

Product Details anti-TUFM Antibody

Target: TUFM (Tufm) (Tu Translation Elongation Factor, Mitochondrial (Tufm))

Binding Specificity: AA 75-104, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUFM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This TUFM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human TUFM.

Clone: RB20864

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-TUFM antibody (ABIN389459)

He, Guo, Liu, Li, Hu, Wang, Song: "TUFM downregulation induces epithelial-mesenchymal transition and invasion in lung cancer cells via a mechanism involving AMPK-GSK3β signaling." in: Cellular and molecular life sciences : CMLS, Vol. 73, Issue 10, pp. 2105-21, (2016) (PubMed).

Target Details for TUFM

Target: TUFM (Tufm) (Tu Translation Elongation Factor, Mitochondrial (Tufm))

Alternative Name: TUFM (Tufm Products)

Synonyms: TUFM antibody, D250 antibody, fi06f04 antibody, wu:fi06f04 antibody, zgc:110766 antibody, COXPD4 antibody, EF-TuMT antibody, EFTU antibody, P43 antibody, 2300002G02Rik antibody, C76308 antibody, C76389 antibody, Tu translation elongation factor, mitochondrial antibody, TUFM antibody, tufm antibody, Tufm antibody

Background: TUFM is a protein which participates in protein translation in mitochondria. This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Molecular Weight: 49542

Gene ID: 7284

NCBI Accession: NP_003312

UniProt: P49411