Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ABCB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-746 amino acids from the C-terminal region of human ABCB7.
CG7955 antibody, Dmel\\CG7955 antibody, dABCB7 antibody, GB11034 antibody, ABCB7 antibody, fc20c02 antibody, wu:fc20c02 antibody, ABC7 antibody, ASAT antibody, Atm1p antibody, EST140535 antibody, AA517758 antibody, AU019072 antibody, Abc7 antibody, ATP binding cassette subfamily B member 7 antibody, ATP-binding cassette sub-family B member 7, mitochondrial antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 7 antibody, ATP-binding cassette sub-family B member 7, mitochondrial-like antibody, ABCB7 antibody, LOC412749 antibody, abcb7 antibody, LOC100367778 antibody, LOC100467128 antibody, Abcb7 antibody
Background
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.